GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs433598 | 1 | rs396508 | chr16:20682354 | ACSM1 | chr16:20634559-20709066:- | -0.22 | -4.21 | 3.19E-5 | Schizophrenia |
| BLCA | cis | rs9457247 | 1 | rs397713 | chr6:167386714 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.04 | 7.23E-7 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs398278 | chr6:167388169 | RNASET2 | chr6:167343008-167412795:- | -0.23 | -4.83 | 1.99E-6 | Crohn's disease |
| BLCA | cis | rs39841 | 1 | rs39841 | chr5:96120170 | ERAP1 | chr5:96096515-96149837:- | -0.47 | -8.87 | 2.75E-17 | Inflammatory skin disease |
| BLCA | cis | rs39841 | 1 | rs39841 | chr5:96120170 | ERAP2 | chr5:96211644-96255398:+ | 0.35 | 5.43 | 1.03E-7 | Inflammatory skin disease |
| BLCA | cis | rs9457247 | 1 | rs400063 | chr6:167386592 | RNASET2 | chr6:167343008-167412795:- | -0.23 | -4.95 | 1.11E-6 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs400176 | chr6:167406238 | RNASET2 | chr6:167343008-167412795:- | -0.25 | -5.16 | 4.07E-7 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs400837 | chr6:167411008 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.05 | 7.0E-7 | Crohn's disease |
| BLCA | cis | rs2243480 | 1 | rs402418 | chr7:65509469 | CCT6P1 | chr7:65216092-65228661:+ | 0.32 | 4.38 | 1.51E-5 | Diabetic kidney disease |
| BLCA | cis | rs9457247 | 1 | rs402749 | chr6:167386104 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.04 | 7.23E-7 | Crohn's disease |
| BLCA | cis | rs56322409 | 1 | rs4037 | chr10:97365820 | ENTPD1 | chr10:97471536-97637022:+ | 0.2 | 5 | 8.71E-7 | Blood metabolite levels |
| BLCA | cis | rs9457247 | 1 | rs404222 | chr6:167402150 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.03 | 7.43E-7 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs405553 | chr6:167395058 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.04 | 7.23E-7 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs406095 | chr6:167409087 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.05 | 7.0E-7 | Crohn's disease |
| BLCA | cis | rs2275426 | 1 | rs4073846 | chr1:46462881 | CCDC163P | chr1:45960581-45965646:- | 0.34 | 6.43 | 3.87E-10 | Body mass index |